Mission

The mission of the Human Immunology Core (HIC) Laboratory is to provide state-of-the-art immunoassays to characterize and quantify the human immune response. Assays ranging from 6-color flow cytometry to sequencing the CDR3 domain of the T cell receptor allow investigators at the Sidney Kimmel Comprehensive Cancer Center (SKCCC) to carefully monitor immune responses of cancer patients enrolled in a variety of immunotherapy clinical trials. The tight integration of experience and expertise in phenotypic, functional and molecular approaches allows investigators to build upon their own expertise.

Staff members of the HIC laboratory are available for consultation and assistance with planning, execution, analysis and interpretation of the immunological assays. The HIC Laboratory also serves as an open collaborative unit with services provided to all members of the University. After consultation and at the request of investigators, the Immunological Monitoring Core will also help to develop and standardize new immunological assays that may provide additional insights into the human immune response.